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If concomitant use is warranted, commonly Appraise the individual, notably in the course of treatment method initiation and dose adjustment. Discontinue OPANA ER if serotonin syndrome is suspected.نعم ممكن في بعض الحالات, خاصة إذا كان مترافق مع اضطرابات نفسية أخرىIn patients with creatinine clea